Venocentric Lesions: An MRI Marker of MS?

Venocentric Lesions: An MRI Marker of MS?

From the earliest descriptions of multiple sclerosis (MS), the venocentric characteristic of plaques was noted. Recently, numerous magnetic resonance imaging (MRI) studies have proposed this finding as a prospective biomarker for MS, which might aid in differentiating MS from other diseases with similar MRI findings. High-field MRI studies have shown that penetrating veins can be detected in mo...

Serial MRI in Epidemiology: Seasonal Occurrence of New MS Lesions

lesions and active scans. Significantly higher rates of disease activity in spring/summer compared to autumn/winter are apparent. "active scan" rates reflect relative counts of exams with one or more new lesions Fig.1: Example shows maximum intensity projection of all activity over 3 months with Gd-DTPA (left) and PD-weighted change (center & right) with monthly intervals. Several activity loci...

Manual Segmentation of MS Cortical Lesions Using MRI: A Comparison of 3 MRI Reading Protocols.

BACKGROUND AND PURPOSE Double inversion recovery has been suggested as the MR imaging contrast of choice for segmenting cortical lesions in patients with multiple sclerosis. In this study, we sought to determine the utility of double inversion recovery for cortical lesion identification by comparing 3 MR imaging reading protocols that combine different MR imaging contrasts. MATERIALS AND METH...

Can Ms Lesions Stages Be Distinguished with Mri? a Pa-mri Study

Perivascular spaces in MS patients at 7 Tesla MRI: a marker of neurodegeneration?

BACKGROUND Virchow-Robin spaces (VRS) are associated with vascular and neurodegenerative disease. In multiple sclerosis (MS), VRS have been associated with neuroinflammation. Ultra-high field imaging may be used to gain insight in these contradictory findings. OBJECTIVE The objective of this paper is to analyze VRS in MS patients using high-resolution 7 Tesla (T) MRI. Additionally, we investi...